Ep 208: Making AI a Team Sport with Alteryx CEO Andy MacMillan

Alteryx
7 views September 16, 2026

*208: Making AI a Team Sport with Alteryx CEO Andy MacMillan* In this episode of Alter Everything, Alteryx CEO Andy MacMillan joins host Joshua Burkhow to explore what it takes to move AI from personal experiments to tools an entire team can trust. Andy shares his journey from software developer to CEO, why businesses get stuck in the “single-player” AI trap, and how empowering the people who know the business best can help unlock AI’s potential. Tune in for a candid conversation about curiosity, collaboration, and why your business expertise matters more than ever. Subscribe to the Alter Everything podcast on your favorite podcast app: * *Apple Podcasts*: https://podcasts.apple.com/us/podcast/alter-everything/id1356137854 * *Spotify*: https://open.spotify.com/show/17KLxb23QlvgcbvLiaPck1?si=FWmOQEITRFCQ42smFjOpfA * *Stitcher*: https://www.stitcher.com/podcast/alteryx/alter-everything 0:00 How AI Earns Trust at Work 2:08 Andy MacMillan's Path from Developer to CEO 7:31 Making Enterprise AI Practical 12:12 The Single-Player AI Trap 21:36 From Early Web Tools to Multiplayer AI 29:12 Empowering Business Experts Without Code 34:26 How AI Changes Software Development 40:12 Combining Probabilistic AI with Business Logic 48:18 The Second AI Aha Moment 54:55 Rapid-Fire Questions on Enterprise AI 1:00:54 Building with AI and Scaling Across Teams

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