Cracking "Forever Chemicals" with 1 Million Chips | Jack Hidary, Defense Tech Leadership Conference

SandboxAQ
30,420 views March 6, 2026

Quantitative AI can't scale on its own. It requires deep partnerships. SandboxAQ CEO Jack Hidary explains how collaboration with Amazon Web Services enabled a breakthrough in breaking down PFAS, or so-called “forever chemicals:" harmful and persistent compounds long thought impossible to degrade. By combining SandboxAQ’s large quantitative models (LQMs) with AWS infrastructure (and over a million cores), the team tackled one of chemistry’s hardest problems, with implications for both defense and private industry. Hidary also discusses collaboration with NVIDIA, an investor and partner in SandboxAQ, including a recent biopharma milestone announced at the 2026 World Economic Forum in Davos. This AI goes beyond language. LQMs are powered by physics, chemistry, and serious compute. Read Jack's Op-Ed about Quantitative AI on the Wall Street Journal or our website: https://www.wsj.com/opinion/america-needs-ai-that-can-do-math-392b223b https://www.sandboxaq.com/post/america-needs-ai-for-the-real-world #sandboxaq #lqms

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